Montelukast belongs to the class of medicines known as leukotriene receptor antagonists (LTRAs).This relaxes the airways, relieves edema, and dampens down redness and irritation. By blocking these receptors, montelukast inhibits the actions of LTD-4 and prevents the development of edema, smooth muscle constriction, and inflammation. These receptors are affected by substances called cysteinyl leukotrienes (LTDs), which are released during inflammation and following exposure to an allergen. Montelukast inhibits specific receptors in the airways called cysteinyl leukotriene (CysLT) receptors, specifically CysLT-1.It inhibits bronchoconstriction, which is the narrowing of the airways resulting in breathing difficulties. Montelukast may be used for the treatment of asthma or allergic rhinitis.Your doctor will be able to explain all possible uses, dosages, precautions, interactions with other drugs, and other potential adverse effects, and you should always talk to them about any kind of medication you are taking, thinking about taking or wanting to stop taking.Medically reviewed by Carmen Fookes, BPharm.
In no circumstances should this article be relied upon without independent consideration and confirmation by a qualified medical practitioner. This article may not always be up to date and is not exhaustive of all of the risks and considerations relevant to this particular drug.
DO I NEED TO TAKE CLARITIN WITH FOOD PROFESSIONAL
It is therefore important for you to note that the information contained in this article does not constitute professional medical or healthcare advice, diagnosis or recommendation of treatment and is not intended to, nor should be used to, replace professional medical advice. However, we can’t replace the one-to-one advice of a qualified medical practitioner or outline all of the possible risks associated with this particular drug and your circumstances. Here at HealthMatch, we’ve done our best to ensure that the information provided in this article is helpful, up to date, and, most importantly, accurate. Prescription to over-the-counter (OTC) switch list | U.S. Onset of action for loratadine tablets for the symptomatic control of seasonal allergic rhinitis in adults challenged with ragweed pollen in the environmental exposure unit: A post hoc analysis of total symptom score (2018) Assess your body’s handling of loratadine before you consume alcohol and engage in any activities requiring alertness.²²Ģ0-641S007 loratadine final print label (2000)Ĭlaritin product line English product monograph | However, because sedation is a known side effect of both substances, you should exercise caution if you consume alcohol while taking loratadine. In a study looking at the effects of combining loratadine and alcohol, researchers found that loratadine did not potentiate the effects of alcohol. Can I drink alcohol while taking loratadine? If you take any of the medications listed above, speak with your doctor about how or if you can take loratadine safely. This is not a complete list of the medicines that might interact with loratadine, so be sure to tell your doctor everything you’re taking.
Migraine medicines, including lasmiditan (Reyvow) Gastrointestinal medicines, including cimetidine (Tagamet) and metoclopramide intranasal (Gimoti)Īntibiotics, including clarithromycin (Biaxin), erythromycin, rifampin, and rifabutin (Mycobutin)Ĭancer drugs, such as everolimus (Zortress, Afinitor), erdafitinib (Balversa), sotorasib (Lumakras), and tepotinib (Tepmetko)Īntidepressants, such as isocarboxazid (Marplan) and tranylcypromine (Parnate) Other allergy medicines, including olopatadine intranasal (Patanase)Īnti-seizure medicines, such as carbamazepine (Tegretol) Loratadine may interact with the following medications:²¹ However, you should check with your doctor if you take any medication that affects the CYP450 enzyme pathway because you may need to use a different antihistamine instead.²⁰ There is no evidence of dangerous and significant drug interactions.
Seek emergency medical assistance if your symptoms are severe. Speak with your doctor if you experience anything unusual while taking loratadine. These lists of potential side effects are not exhaustive. Heart palpitations, abnormal heart rhythm
Other reported adverse effects include the following:¹⁵ ¹⁶ Less commonly, the following side effects may occur, some due to the anticholinergic effects of loratadine:¹⁴ Most of them are mild and resolve without treatment.¹² ¹³Ĭommon and less severe side effects of loratadine include the following: Loratadine is considered to be safe and effective, but some people experience side effects.
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